Effect of prophylactic colchicine therapy on leukocyte function in patients with familial mediterranean fever
نویسندگان
چکیده
منابع مشابه
Colchicine concentration in leukocytes of patients with familial Mediterranean fever.
Free and total plasma, granulocyte and mononuclear cell colchicine concentrations were measured by radioimmunoassay in 30 patients with familial Mediterranean fever treated with colchicine 0.5 to 2 mg day-1. Colchicine concentrations showed a large intersubject variability in plasma (0.13-1.75 ng ml-1), granulocytes (4 to 64 ng/10(9) cells), and mononuclear cells (11.4 to 57.6 ng/10(9) cells). ...
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BACKGROUND [corrected] Colchicine is widely used for treating gout and familial Mediterranean fever. However, studies in animal models have reported ill effects of colchicine on the central nervous system, including cognitive function. OBJECTIVES To evaluate the cognitive status of elderly FMF patients on long-term colchicine treatment. METHODS The study group consisted of 55 FMF patients a...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1976
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780190315